Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776051 | 0.83 | CACNA1G (0.46) | CHRM4HSP90AB1MAPTCACNA1GALDH1A1 | |
| SCHEMBL4778842 | 0.80 | HSP90AB1 (0.40) | CHRM4HSP90AB1MAPTCACNA1GKDM4E | |
| SCHEMBL19095368 | 0.77 | MAPT (0.47) | CHRM4HSP90AB1MAPTCACNA1GALDH1A1 | |
| SCHEMBL17432438 | 0.70 | PPARD (0.49) | CHRM4MAPTCACNA1GKDM4EALDH1A1 | |
| SCHEMBL19538665 | 0.69 | TSHR (0.68) | CHRM4MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL19095372 | 0.69 | ALDH1A1 (0.43) | CHRM4HSP90AB1MAPTCACNA1GKDM4E | |
| SCHEMBL5536931 | 0.68 | KCNA5 (0.53) | CHRM4MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL22963896 | 0.67 | HRH3 (0.58) | CHRM4PPARDPPARAKCNA5 | |
| SCHEMBL5534678 | 0.67 | KMT2A (0.52) | CHRM4ALDH1A1MEN1KMT2APPARD | |
| SCHEMBL5534516 | 0.66 | ALDH1A1 (0.62) | CHRM4MAPTALDH1A1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275035-A1 | Nitroimidazole Compounds | JIRICEK JAN | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275035-A1 | Nitroimidazole Compounds | NQO2, NQO1, MT-ND2 | CHRM4 2666/4885HSP90AB1 772/4885MAPT 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.