Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758359 | 0.84 | NOS1 (0.44) | NOS1PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL3760895 | 0.84 | MPO (0.40) | NOS1PIK3CGPIK3CAMPOPTPN1 | |
| SCHEMBL3755307 | 0.83 | PTPN1 (0.44) | NOS1MPOGAAL3MBTL1NUDT1 | |
| SCHEMBL3760969 | 0.81 | L3MBTL1 (0.47) | NOS1MPOGAAL3MBTL1PTPN1 | |
| SCHEMBL4781184 | 0.77 | NOS1 (0.38) | ALOX5APFEN1NOS1PIK3CGPIK3CA | |
| SCHEMBL3760847 | 0.77 | NOS1 (0.44) | NOS1PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL3755253 | 0.77 | GRIN2B (0.39) | NOS1PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL3765540 | 0.77 | MPO (0.38) | ALOX5APFEN1NOS1PIK3CGPIK3CA | |
| SCHEMBL3764208 | 0.77 | PIK3CG (0.49) | NOS1PIK3CGPIK3CAPIK3CBHDAC6 | |
| SCHEMBL4450439 | 0.76 | NOS1 (0.46) | NOS1PIK3CGPIK3CAPIK3CBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009079-A2 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |