Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117233 | 0.95 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2AGAACYP2C9 | |
| SCHEMBL29117235 | 0.95 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2AGAACYP2C9 | |
| SCHEMBL28586012 | 0.89 | MAPK1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1EPHX2 | |
| SCHEMBL3756652 | 0.89 | MAPK1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1EPHX2 | |
| SCHEMBL4270527 | 0.89 | MAPK1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1EPHX2 | |
| SCHEMBL2146121 | 0.86 | EPHX2 (0.58) | ALDH1A1KMT2AGAAMAPK1L3MBTL1 | |
| SCHEMBL23210482 | 0.81 | ITGB3 (0.43) | ALDH1A1KDM4EGAACYP2C9CYP2C19 | |
| SCHEMBL3461854 | 0.81 | ITGB3 (0.43) | ALDH1A1KDM4EGAACYP2C9CYP2C19 | |
| SCHEMBL314947 | 0.81 | ITGB3 (0.43) | ALDH1A1KDM4EGAACYP2C9CYP2C19 | |
| SCHEMBL15085132 | 0.81 | BCHE (0.50) | ALDH1A1KDM4EKMT2AGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036021-A1 | TETRAHYDRO-LH-PYRIDO [3,4 -B] INDOLE DERIVATIVES AS CBL RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2008-03-27 | — | — | WO | disclosed |