Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 4/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC1R | Q01726 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779421 | 1.00 | MCHR1 (0.34) | MCHR1ALDH1A1GAAMC4RKIF11 | |
| SCHEMBL4020281 | 0.93 | EED (0.34) | MCHR1ALDH1A1GAAMC4RMEN1 | |
| SCHEMBL4019099 | 0.91 | ALDH1A1 (0.35) | MCHR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4023939 | 0.89 | MCHR1 (0.37) | MCHR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4028159 | 0.87 | ALDH1A1 (0.39) | MCHR1ALDH1A1GAAKIF11MEN1 | |
| SCHEMBL4025011 | 0.86 | MCHR1 (0.30) | MCHR1 | |
| SCHEMBL4779411 | 0.86 | MC4R (0.34) | MCHR1ALDH1A1GAAMC4RMEN1 | |
| SCHEMBL4026452 | 0.78 | ALDH1A1 (0.40) | MCHR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4772648 | 0.76 | KIF11 (0.44) | ALDH1A1KIF11MEN1KMT2ALMNA | |
| SCHEMBL4021692 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAAKIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |