Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297660 | 0.90 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL4303026 | 0.88 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4775988 | 0.85 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4775755 | 0.83 | KCNH2 (0.41) | KCNH2HTR2A | |
| SCHEMBL4778712 | 0.83 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL2798116 | 0.82 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL4779527 | 0.82 | KCNH2 (0.46) | KCNH2NR1H4HTR2A | |
| SCHEMBL4778509 | 0.82 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL2800239 | 0.80 | LMNA (0.40) | — | |
| SCHEMBL4779477 | 0.80 | KCNH2 (0.57) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |