Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29571304 | 1.00 | TSHR (0.63) | TSHRP2RX7HTTALDH1A1HSD17B10 | |
| SCHEMBL19852373 | 0.88 | ALDH1A1 (0.64) | TSHRP2RX7HTTALDH1A1HSD17B10 | |
| SCHEMBL28216192 | 0.88 | P2RX7 (0.60) | TSHRP2RX7HTTALDH1A1L3MBTL1 | |
| SCHEMBL28937318 | 0.86 | P2RX7 (0.58) | TSHRP2RX7HTTALDH1A1L3MBTL1 | |
| SCHEMBL6043587 | 0.84 | TSHR (0.61) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL162019 | 0.84 | TSHR (0.61) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL1737254 | 0.84 | BRD4 (0.61) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL29870373 | 0.84 | BRD4 (0.61) | TSHRHTTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL49913 | 0.83 | POLB (0.66) | TSHRHTTALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL844745 | 0.83 | TSHR (0.59) | TSHRHTTALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018368-A1 | COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2009-02-05 | — | — | WO | claimed |
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | claimed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | claimed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | claimed |
| EP-4192833-B1 | PHARMACOLOGICALLY ACTIVE HETEROCYCLIC-SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2026-01-21 | — | — | EP | disclosed |
| US-12473293-B2 | Pharmacologically active heterocyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives | RICHTER GEDEON NYRT. (HU) | 2025-11-18 | — | — | US | disclosed |
| US-12422399-B2 | Systems, devices, and methods for gas sensing | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20250287942-A1 | FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-09-18 | — | — | US | disclosed |
| WO-2024262824-A1 | NOVEL PROCESS FOR SYNTHESIS OF POLYSUBSTITUTED PYRIDINE DERIVATIVES | 서울대학교산학협력단 | 2024-12-26 | — | — | WO | disclosed |
| US-20240353369-A1 | SYSTEMS, DEVICES, AND METHODS FOR GAS SENSING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-10-24 | — | — | US | disclosed |
| US-12013367-B2 | Monolithic 3D integrated circuit for gas sensing and method of making and system using | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-06-18 | — | — | US | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| US-4526941-A | Contacting alpha olefin with catalyst comprising organomagnesium compound, titanium compound, nitrogen or sulfur heterocyclic compound, slurry component and organometallic component | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-07-02 | — | — | US | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4350819-A | 1-Hydroxypyrazole | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0052471-A1 | Process and catalyst for polymerization of olefins | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-05-26 | — | — | EP | disclosed |
| US-4330650-A | HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4329349-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4255280-A | ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4009174-A | VASODILATORS | THE BOOTS COMPANY LIMITED (EN) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | TSHR 2144/4885P2RX7 810/4885HTT 3899/4885 |
| US-20250287942-A1 | FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS | ACHE, BCHE, DDT | TSHR 4454/4885P2RX7 3117/4885HTT 1017/4885 |
| US-12473293-B2 | Pharmacologically active heterocyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives | GABRA5, GABRA1, P2RX5 | TSHR 856/4885P2RX7 23/4885HTT 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.