Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | PTH1R | Q03431 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774136 | 0.91 | TERT (0.47) | TERTTAAR1KLK1KLK5FPR2 | |
| SCHEMBL9666999 | 0.83 | TAAR1 (0.70) | TERTTAAR1KLK1KLK5TBXAS1 | |
| SCHEMBL4776719 | 0.83 | TAAR1 (0.70) | TERTTAAR1KLK1KLK5FPR2 | |
| SCHEMBL4778364 | 0.81 | TERT (0.58) | TERTTAAR1KLK1KLK5FPR2 | |
| SCHEMBL11411805 | 0.76 | ESR1 (0.52) | TERTTAAR1TTBK1TTBK2TBXAS1 | |
| SCHEMBL6572107 | 0.75 | TERT (0.47) | TERTTAAR1KLK1KLK5FPR2 | |
| SCHEMBL8309447 | 0.73 | TBXAS1 (0.49) | TERTTAAR1TTBK1TTBK2TBXAS1 | |
| SCHEMBL6017533 | 0.73 | TBXAS1 (0.53) | TERTTAAR1TBXAS1KDM4EALDH1A1 | |
| SCHEMBL12807572 | 0.73 | TERT (0.66) | TERTTAAR1TBXAS1NAMPT | |
| SCHEMBL4779375 | 0.72 | TERT (0.47) | TERTTAAR1KLK1KLK5TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |