Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2115265 | 0.97 | AOC3 (0.56) | AOC3ALDH1A1TSHRCA2CARM1 | |
| Hydrochloric Acid SCHEMBL3895103 | 0.97 | AOC3 (0.56) | AOC3ALDH1A1TSHRCA2CARM1 | |
| SCHEMBL4541170 | 0.81 | AOC3 (0.41) | AOC3ALDH1A1CA2NPC1RAB9A | |
| SCHEMBL640126 | 0.78 | ALDH1A1 (0.55) | AOC3ALDH1A1TSHRCA2MGLL | |
| SCHEMBL39645 | 0.78 | CYP1A2 (0.55) | AOC3ALDH1A1TSHRCA2MGLL | |
| SCHEMBL833414 | 0.78 | AOC3 (0.64) | AOC3ALDH1A1TSHRCA2CARM1 | |
| SCHEMBL2219958 | 0.78 | AOC3 (0.64) | AOC3ALDH1A1TSHRCA2CARM1 | |
| SCHEMBL1794281 | 0.78 | AOC3 (0.64) | AOC3ALDH1A1TSHRCA2CARM1 | |
| Hydrochloric Acid SCHEMBL11779718 | 0.76 | AOC3 (0.61) | AOC3ALDH1A1TSHRCA2CARM1 | |
| Bromide SCHEMBL209320 | 0.76 | ALDH1A1 (0.52) | AOC3ALDH1A1TSHRCA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130066-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024130064-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024130065-A1 | SUBSTITUTED DIHYDROPYRROLO[3, 4-D]PYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024130062-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| EP-4225310-A1 | HETEROARYL AMIDE INHIBITORS OF CD38 | Napa Therapeutics Ltd. (VG) | 2023-08-16 | — | — | EP | disclosed |
| CN-113574041-A | Method for producing bisphenol and method for producing polycarbonate resin | 三菱化学株式会社 | 2021-10-29 | — | — | CN | disclosed |
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Nerviano Medical Sciences, S.R.L. (IT) | 2021-09-30 | — | — | US | disclosed |
| CN-110382479-A | The fluoro- 3- hydroxyl propyl- 2- base ester derivative of carbamic acid 1,1,1- tri- as MAGL inhibitor | 辉瑞大药厂 | 2019-10-25 | — | — | CN | disclosed |
| CN-110234638-A | Heteroaryl phenoxy benzamide KAPPA opiates ligand | 辉瑞大药厂 | 2019-09-13 | — | — | CN | disclosed |
| CN-110198944-A | Heterocyclic ring spiroring compounds as monoacylglycerol lipase inhibitor | 辉瑞大药厂 | 2019-09-03 | — | — | CN | disclosed |
| EP-1991587-A2 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | ProChon Biotech Ltd. (IL) | 2008-11-19 | — | — | EP | disclosed |
| CN-101119969-A | Aryl and heteroaryl substituted tetrahydroisoquinolines and their use to block reuptake of norepinephrine, dopamine, and serotonin | AMR TECHNOLOGY INC (US) | 2008-02-06 | — | — | CN | disclosed |
| US-20080010692-A1 | Mammals carrying functional single nucleotide polymorphisms in brain-specific tryptophan hydroxylase | DUKE UNIVERSITY | 2008-01-10 | — | — | US | disclosed |
| WO-2007102149-A2 | HYDRAZIDO DERIVATIVES OF HYALURONIC ACID | PROCHON BIOTECH LTD. (IL) | 2007-09-13 | — | — | WO | disclosed |
| CN-1782086-A | Adeno-associated virus mediating trigenic cell expression system | CAPITAL MEDICAL UNIV (CN) | 2006-06-07 | — | — | CN | disclosed |
| CN-1102386-C | 5-HT uptake inhibitors and selective 5-HT1ACompositions of antagonists | ASTRA AG (SE) | 2003-03-05 | — | — | CN | disclosed |
| CN-1187768-A | Combination of 5-HT uptake inhibitors and selective 5-HT 1A antagonists | ASTRA AB (SE) | 1998-07-15 | — | — | CN | disclosed |
| WO-1996012706-A1 | NOVEL ACID PYRAZOLE AND PYRAZOLONE DERIVATIVES FOR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1996-05-02 | — | — | WO | disclosed |
| WO-1995027489-A1 | COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-10-19 | — | — | WO | disclosed |
| WO-1982000143-A1 | HETEROCYCLIC COMPOUNDS,METHOD FOR PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1982-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP4K2 | AOC3 4403/4885ALDH1A1 3081/4885TSHR 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.