SCHEMBL833414

SCHEMBL833414

NN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 5/20 0.64
ALDH1A1 P00352 2/20 0.55
TSHR P16473 2/20 0.55
CA2 P00918 1/20 0.50
CARM1 Q86X55 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
PRMT8 Q9NR22 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.48
CALM1 P0DP23 1/20 0.45
CYP2A6 P11509 1/20 0.43
HTR2A P28223 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
CYP2C19 P33261 1/20 0.43
MGLL Q99685 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1794281 1.00 AOC3 (0.64) AOC3ALDH1A1TSHRCA2CARM1
Hydrochloric Acid SCHEMBL11779718 0.97 AOC3 (0.61) AOC3ALDH1A1TSHRCA2CARM1
SCHEMBL17454767 0.88 MAOB (0.60) AOC3ALDH1A1TSHRCA2LOXL2
SCHEMBL17196392 0.88 TAAR1 (0.59) AOC3ALDH1A1TSHRCA2TAAR1
SCHEMBL16257816 0.85 AOC3 (0.54) AOC3ALDH1A1TSHRCA2CARM1
SCHEMBL1795445 0.85 AOC3 (0.63) AOC3ALDH1A1TSHRCA2CARM1
SCHEMBL1795448 0.85 AOC3 (0.63) AOC3ALDH1A1TSHRCA2CARM1
Glycine SCHEMBL3882403 0.84 AOC3 (0.48) AOC3ALDH1A1TSHRCA2CARM1
SCHEMBL17285436 0.83 AOC3 (0.67) AOC3ALDH1A1TSHRCA2CARM1
SCHEMBL2219958 0.82 AOC3 (0.64) AOC3ALDH1A1TSHRCA2CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO claimed
CN-118851946-A Method for preparing long fatty chain diacid derivative and application thereof 广东东阳光药业股份有限公司 2024-10-29 CN claimed
CN-118409029-A Derivatization HPLC method for separating and measuring impurity hydrazine in carbidopa-levodopa sustained release tablet 重庆华邦制药有限公司 2024-07-30 CN claimed
CN-116640415-A Recyclable epoxy resin, system material, composite material and recycling method thereof 道生天合材料科技(上海)股份有限公司 2023-08-25 CN claimed
CN-114805114-A Preparation method of ubenimex genotoxic impurity 上海秀新臣邦医药科技有限公司 2022-07-29 CN claimed
CN-111333505-B Method for preparing long-chain fatty diacid monobenzyl ester and application thereof 东莞市东阳光生物药研发有限公司 2022-07-26 CN claimed
CN-114428141-A Method for detecting content of free hydrazine impurities in isoniazid 北京民康百草医药科技有限公司 2022-05-03 CN claimed
CN-111333505-A Method for preparing long-chain fatty diacid monobenzyl ester and application thereof 东莞市东阳光生物药研发有限公司 2020-06-26 CN claimed
EP-2651420-B1 PEPTIDE-BASED IN VIVO SIRNA DELIVERY SYSTEM ARROWHEAD PHARMACEUTICALS INC (US) 2018-10-03 EP claimed
EP-2651420-A2 PEPTIDE-BASED IN VIVO SIRNA DELIVERY SYSTEM Arrowhead Research Corporation (US) 2013-10-23 EP claimed
US-20120165393-A1 Peptide-Based In Vivo siRNA Delivery System Arrowhead Madison Inc. (US) 2012-06-28 US claimed
WO-2012083185-A2 PEPTIDE-BASED IN VIVO SIRNA DELIVERY SYSTEM ARROWHEAD RESEARCH CORPORATIONS (US) 2012-06-21 WO claimed
US-20100105704-A1 7-(3',4'-Dialkoxyphenyl)-[1,2,4]-Triazolo[1,5-A]Pyrimidine Compounds, Process for Preparing Thereof, and Pharmaceutical Composition for Treating or Preventing Asthma, Chronic Obstructive Pulmonary Disease, Arthritis, Atopic Dermatitis, Tumor and Degenerative Brain Diseases Comprising the Same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2010-04-29 US claimed
WO-2008117943-A1 7-(3',4'-DIALKOXYPHENYL)-[1,2,4]-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS, PROCESS FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ARTHRITIS, ATOPIC DERMATITIS, TUMOR AND DEGENERATIVE BRAIN DISEASES COMPRISING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-10-02 WO claimed
US-5272242-A Hydrazino/polyhydrosilazanes ATOCHEM (FR) 1993-12-21 US claimed
EP-0359604-A1 Process for preparing polyhydrosilazanes from hydrazines, and their use as precursors for ceramics ELF ATOCHEM S.A. (FR) 1990-03-21 EP claimed
CN-1040380-A Preparation is by the application as the precursor of ceramic product of the method for the poly-hydrogen silazane of hydrazine derivative and described silazane ATOCHEM (FR) 1990-03-14 CN claimed
EP-0351262-A1 Polysilazanes, their preparation and use as precursors for ceramic materials, and the ceramic materials ELF ATOCHEM S.A. (FR) 1990-01-17 EP claimed
CN-1038655-A Polysilazane, its preparation method, and use it for ceramic precursor and make described pottery ATOCHEM (FR) 1990-01-10 CN claimed
EP-0327773-A1 Polysiloxazanes, process for producing same and their use as precursors for ceramics and ceramic materials ELF ATOCHEM S.A. (FR) 1989-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105704-A1 7-(3',4'-Dialkoxyphenyl)-[1,2,4]-Triazolo[1,5-A]Pyrimidine Compounds, Process for Preparing Thereof, and Pharmaceutical Composition for Treating or Preventing Asthma, Chronic Obstructive Pulmonary Disease, Arthritis, Atopic Dermatitis, Tumor and Degenerative Brain Diseases Comprising the Same TSLP, IL5, ADORA1 AOC3 325/4885ALDH1A1 604/4885TSHR 4458/4885
US-20120165393-A1 Peptide-Based In Vivo siRNA Delivery System VIP, RNASE1, APLNR AOC3 4535/4885ALDH1A1 4866/4885TSHR 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.