Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916164 | 0.83 | F2 (0.60) | ALDH1A1TSHRSMN1; SMN2LMNAF2 | |
| SCHEMBL29787109 | 0.83 | F2 (0.60) | ALDH1A1TSHRSMN1; SMN2LMNAF2 | |
| SCHEMBL28776101 | 0.83 | CHRNB2 (0.52) | ALDH1A1TSHRLMNAF2MAOB | |
| SCHEMBL28472004 | 0.82 | F2 (0.58) | ALDH1A1TSHRSMN1; SMN2LMNAF2 | |
| SCHEMBL27606934 | 0.81 | BCL9 (0.54) | ALDH1A1TSHRSMN1; SMN2LMNAF2 | |
| SCHEMBL1417762 | 0.80 | MAPK1 (0.53) | ALDH1A1SMN1; SMN2MAOBCES2CES1 | |
| SCHEMBL7069628 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAF2MAOB | |
| SCHEMBL27631882 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2LMNAF2 | |
| SCHEMBL8950084 | 0.77 | CHRNB2 (0.43) | ALDH1A1F2MAOBCHRNB2CHRNA4 | |
| Dinitrophenylene SCHEMBL27724274 | 0.77 | TSHR (0.77) | ALDH1A1TSHRSMN1; SMN2LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |