Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069631 | 0.87 | BCL9 (0.56) | ALDH1A1GAAHPGDTDP1CYP2C9 | |
| SCHEMBL4608246 | 0.86 | BCL9 (0.55) | ALDH1A1GAAHPGDTDP1CYP2C9 | |
| SCHEMBL9168629 | 0.86 | BCL9 (0.55) | ALDH1A1GAAHPGDTDP1CYP2C9 | |
| SCHEMBL4073813 | 0.84 | BCL9 (0.58) | ALDH1A1GAATDP1LMNAKMT2A | |
| SCHEMBL8359279 | 0.79 | EPHX2 (0.55) | — | |
| SCHEMBL4076672 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDTDP1LMNABCL9 | |
| SCHEMBL4779903 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19LMNACHRNB2 | |
| SCHEMBL9065260 | 0.77 | CES2 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4849025 | 0.77 | BCL9 (0.68) | ALDH1A1LMNACHRNB2CHRNA4MEN1 | |
| SCHEMBL8461839 | 0.76 | CHRNB2 (0.67) | ALDH1A1HPGDLMNACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |