Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262856 | 0.87 | GAA (0.72) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL4004500 | 0.84 | LIPE (0.58) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL14389801 | 0.83 | GAA (0.51) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL27795067 | 0.83 | ALDH1A1 (0.82) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL14389786 | 0.81 | GAA (0.49) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL10669648 | 0.81 | ALOX15 (0.61) | ALOX15GAARAB9ANPC1FAAH | |
| SCHEMBL27627256 | 0.80 | ALOX15 (0.56) | ALOX15ALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL5433602 | 0.80 | ALOX15 (0.56) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL1243015 | 0.80 | ALOX15 (0.47) | ALOX15ALDH1A1POLBGAARAB9A | |
| SCHEMBL8223160 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012622-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |