Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 16/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472824 | 0.81 | KDM4E (0.40) | BDKRB1POLBGAATSHRBMP1 | |
| SCHEMBL4778653 | 0.79 | RAPGEF4 (0.36) | BDKRB1BMP1 | |
| SCHEMBL4794418 | 0.78 | RAPGEF4 (0.37) | BDKRB1TSHRBMP1 | |
| SCHEMBL4477913 | 0.78 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL14304908 | 0.77 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL14304906 | 0.76 | BDKRB1 (0.56) | BDKRB1 | |
| SCHEMBL14311115 | 0.76 | BDKRB1 (0.58) | BDKRB1POLB | |
| SCHEMBL10008677 | 0.75 | FABP4 (0.48) | BDKRB1POLBGAATSHR | |
| SCHEMBL14304913 | 0.75 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL700853 | 0.74 | BDKRB1 (0.62) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002849-A2 | ARYL SULFONES | NEUROGEN CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008002849-A2 | ARYL SULFONES | NEUROGEN CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |