Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780362 | 0.81 | BDKRB1 (0.40) | POLBBDKRB1GAATSHRBMP1 | |
| SCHEMBL10008677 | 0.80 | FABP4 (0.48) | ALDH1A1POLBTDP1BDKRB1GAA | |
| SCHEMBL4472823 | 0.78 | KDM4E (0.39) | KDM4EPOLBTDP1BDKRB1GAA | |
| SCHEMBL571406 | 0.78 | BDKRB1 (0.37) | KDM4EPOLBTDP1BDKRB1GAA | |
| SCHEMBL15347788 | 0.77 | BDKRB1 (0.37) | KDM4EPOLBTDP1BDKRB1GAA | |
| SCHEMBL4477913 | 0.75 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL700853 | 0.72 | BDKRB1 (0.62) | BDKRB1 | |
| SCHEMBL15347791 | 0.71 | BDKRB1 (0.61) | BDKRB1 | |
| SCHEMBL4472820 | 0.70 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL14048055 | 0.68 | NR3C1 (0.41) | KDM4EPOLBGAATSHRBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538111-B2 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2009-05-26 | — | — | US | disclosed |
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LTB4R2, BDKRB2, TBXA2R | KDM4E 2998/4885ALDH1A1 283/4885POLB 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.