Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MDH2 | P40926 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779291 | 0.91 | KIF11 (0.36) | KIF11KDM4EMAPTCFTRMEN1 | |
| SCHEMBL4845571 | 0.79 | PPARG (0.49) | MAPTALDH1A1PPARGMAOB | |
| SCHEMBL27516237 | 0.77 | MAPT (0.51) | KDM4EMAPTCFTRMEN1ALDH1A1 | |
| SCHEMBL1130751 | 0.74 | PPARG (0.49) | KDM4EMAPTCFTRPPARGMAOB | |
| SCHEMBL8304179 | 0.68 | MCL1 (0.41) | KDM4EMAPTCFTRMEN1ALDH1A1 | |
| SCHEMBL8309388 | 0.67 | PPARG (0.44) | KDM4EMAPTCFTRMEN1ALDH1A1 | |
| SCHEMBL24398177 | 0.66 | KIF11 (0.71) | KIF11KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8857154 | 0.65 | PPARG (0.43) | KDM4EMAPTCFTRMEN1ALDH1A1 | |
| SCHEMBL7833699 | 0.65 | PPARG (0.33) | KDM4EMAPTPPARG | |
| SCHEMBL8305019 | 0.64 | RECQL (0.42) | KDM4EMAPTALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |