Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780386 | 0.91 | KIF11 (0.34) | KIF11KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL4773524 | 0.72 | PPARG (0.53) | MAPTALDH1A1PPARG | |
| SCHEMBL4778011 | 0.70 | CA2 (0.60) | KIF11KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL4845571 | 0.68 | PPARG (0.49) | MAPTALDH1A1PPARG | |
| SCHEMBL8857154 | 0.67 | PPARG (0.43) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8305019 | 0.66 | RECQL (0.42) | KDM4EMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27924999 | 0.63 | AHR (0.47) | KIF11KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL17274741 | 0.62 | AHR (0.55) | KIF11KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL19768708 | 0.62 | AHR (0.59) | KIF11KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL31324185 | 0.62 | KDM4E (0.83) | KDM4EMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |