Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584666 | 0.77 | PLA2G2A (0.55) | PLA2G2APTGDR2FOLH1PLA2G1BGFER | |
| SCHEMBL5385729 | 0.77 | CNR2 (0.46) | PLA2G2ACYP19A1P2RX4SMN1; SMN2MAPT | |
| SCHEMBL4881610 | 0.77 | FOLH1 (0.55) | PLA2G2APTGDR2FOLH1PLA2G1BGFER | |
| SCHEMBL8173620 | 0.76 | FOLH1 (0.64) | PLA2G2APTGDR2FOLH1PLA2G1BGFER | |
| SCHEMBL5413326 | 0.75 | CYP19A1 (0.43) | PLA2G2AGFERCYP19A1P2RX4SMN1; SMN2 | |
| SCHEMBL13802422 | 0.75 | PTGDR2 (0.76) | PLA2G2APTGDR2PLA2G1BGFERTHRA | |
| SCHEMBL9584407 | 0.74 | FOLH1 (0.52) | PLA2G2APTGDR2FOLH1PLA2G1BGFER | |
| SCHEMBL4209387 | 0.74 | PTGDR2 (0.74) | PLA2G2APTGDR2PLA2G1BGFERTHRA | |
| Water SCHEMBL9584494 | 0.73 | PTGDR2 (0.51) | PLA2G2APTGDR2FOLH1PLA2G1BGFER | |
| SCHEMBL13802405 | 0.73 | PTGDR2 (0.70) | PLA2G2APTGDR2PLA2G1BGFERTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931632-A2 | USEFUL INDOLE COMPOUNDS | Microbia Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |