Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 17/20 | 0.38 |
| ▸ | RAF1 | P04049 | 9/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780448 | 0.91 | RAF1 (0.43) | PLAUBRAFRAF1 | |
| SCHEMBL4778219 | 0.86 | NAPEPLD (0.40) | PLAUBRAFRAF1 | |
| SCHEMBL4779575 | 0.86 | ACKR3 (0.34) | BRAF | |
| SCHEMBL4782767 | 0.86 | CNR2 (0.42) | PLAUBRAFRAF1 | |
| SCHEMBL4783530 | 0.85 | ACKR3 (0.34) | BRAF | |
| SCHEMBL4782171 | 0.85 | PLAU (0.38) | PLAUBRAFRAF1 | |
| SCHEMBL4781149 | 0.85 | PLAU (0.40) | PLAUBRAFRAF1CFTR | |
| SCHEMBL4781339 | 0.84 | BRAF (0.43) | BRAFRAF1 | |
| SCHEMBL4782030 | 0.84 | PLAU (0.47) | PLAUBRAFRAF1 | |
| SCHEMBL4782131 | 0.84 | PLAU (0.38) | PLAUBRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |