Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 6/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DDT | P30046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783530 | 0.99 | ACKR3 (0.34) | ACKR3ERBB2KLKB1BRAFHTR1A | |
| SCHEMBL4782897 | 0.90 | DDT (0.40) | KLKB1BRAFDDT | |
| SCHEMBL4779581 | 0.90 | MAPK14 (0.39) | BRAFDDT | |
| SCHEMBL4780442 | 0.86 | PLAU (0.38) | BRAF | |
| SCHEMBL4781339 | 0.83 | BRAF (0.43) | BRAFDDT | |
| SCHEMBL4727546 | 0.83 | RAF1 (0.36) | BRAFDDT | |
| SCHEMBL4728307 | 0.83 | RAF1 (0.45) | BRAF | |
| SCHEMBL4782030 | 0.83 | PLAU (0.47) | BRAF | |
| SCHEMBL4782901 | 0.82 | BRAF (0.45) | BRAFDDT | |
| SCHEMBL4778219 | 0.81 | NAPEPLD (0.40) | ACKR3BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |