Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778219 | 0.98 | NAPEPLD (0.40) | CNR2CYP2D6CYP2C19CYP1A2PLAU | |
| SCHEMBL4779984 | 0.90 | ACKR3 (0.41) | CYP2C19CYP1A2PLAUACKR3GLS | |
| SCHEMBL4778221 | 0.88 | RAF1 (0.43) | PLAUBRAFRAF1MAPK14 | |
| SCHEMBL4781496 | 0.88 | ACKR3 (0.40) | PLAUACKR3GLSBRAF | |
| SCHEMBL4782171 | 0.86 | PLAU (0.38) | PLAUBRAFRAF1MAPK14 | |
| SCHEMBL4780442 | 0.86 | PLAU (0.38) | PLAUBRAFRAF1 | |
| SCHEMBL4781149 | 0.85 | PLAU (0.40) | PLAUBRAFRAF1MAPK14 | |
| SCHEMBL4781359 | 0.85 | ACKR3 (0.47) | CNR2PLAUACKR3BRAFRAF1 | |
| SCHEMBL4782308 | 0.85 | PLAU (0.41) | PLAUBRAFRAF1MAPK14 | |
| SCHEMBL4783670 | 0.83 | MAPK14 (0.39) | PLAUPIK3CBBRAFRAF1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |