Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727253 | 0.90 | ROCK1 (0.48) | ROCK2ROCK1MEN1KMT2ARAB9A | |
| SCHEMBL4780086 | 0.81 | ROCK1 (0.54) | ROCK2ROCK1 | |
| SCHEMBL4725670 | 0.80 | ROCK2 (0.55) | ROCK2ROCK1MEN1KMT2ARAB9A | |
| SCHEMBL4780451 | 0.80 | ROCK2 (0.48) | ROCK2ROCK1MEN1KMT2AKDM4E | |
| SCHEMBL4776809 | 0.80 | ROCK1 (0.46) | ROCK2ROCK1RAB9AMAPK1 | |
| SCHEMBL4726466 | 0.79 | ROCK1 (0.49) | ROCK2ROCK1MEN1KMT2ALMNA | |
| SCHEMBL4725195 | 0.79 | LMNA (0.44) | ROCK2ROCK1MEN1KMT2ALMNA | |
| SCHEMBL4778386 | 0.78 | ROCK1 (0.46) | ROCK2ROCK1LMNAKDM4ENPC1 | |
| SCHEMBL4777271 | 0.78 | ROCK1 (0.48) | ROCK2ROCK1LMNASMN1; SMN2AKT3 | |
| SCHEMBL4726382 | 0.78 | ROCK1 (0.46) | ROCK2ROCK1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |