Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530859 | 1.00 | GABRA1 (0.45) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL28680548 | 0.86 | ALDH1A1 (0.53) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL10563836 | 0.85 | GABRA1 (0.42) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL14958374 | 0.85 | TSHR (0.66) | TSHRALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL6464901 | 0.83 | TSHR (0.52) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL28233341 | 0.83 | ALDH1A1 (0.40) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL1538548 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL6257154 | 0.82 | CLCN2 (0.41) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL9199285 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2TSHRALDH1A1CLCN2 | |
| SCHEMBL10915002 | 0.81 | GABRA1 (0.50) | GABRA1GABRB2TSHRALDH1A1CLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013319-A9 | SILICONE RUBBER COMPOSITION, METHOD FOR PRODUCING THE SAME, HEAT-CURABLE SILICONE RUBBER COMPOSITION, AND RUBBER SEALING PART FOR AUTOMOBILES | DOW CORNING TORAY CO LTD (JP) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008013319-A1 | SILICONE RUBBER COMPOSITION, METHOD FOR PRODUCING THE SAME, HEAT-CURABLE SILICONE RUBBER COMPOSITION, AND RUBBER SEALING PART FOR AUTOMOBILES | DOW CORNING TORAY CO., LTD. (JP) | 2008-01-31 | — | — | WO | disclosed |