Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776011 | 0.88 | KMT2A (0.50) | SLC6A4P2RY12MEN1KMT2AALDH1A1 | |
| SCHEMBL4777966 | 0.86 | MEN1 (0.50) | SPHK1KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL4849119 | 0.79 | MEN1 (0.48) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4849122 | 0.79 | MEN1 (0.48) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4846033 | 0.74 | MEN1 (0.36) | P2RY12MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5243868 | 0.74 | LMNA (0.45) | HTR2AHTR1AMEN1KMT2A | |
| SCHEMBL4781622 | 0.74 | MEN1 (0.43) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4780780 | 0.73 | P2RY12 (0.34) | HTR1ASLC6A4P2RY12 | |
| SCHEMBL14290896 | 0.73 | MEN1 (0.37) | KCNH2P2RY12MEN1KMT2AALDH1A1 | |
| SCHEMBL5241842 | 0.73 | LMNA (0.43) | HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |