Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874215 | 0.87 | CCR2 (0.60) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL3874214 | 0.87 | CCR2 (0.60) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL3869036 | 0.87 | DHODH (0.57) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL3869039 | 0.87 | DHODH (0.57) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL28975696 | 0.84 | L3MBTL1 (0.88) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL4780786 | 0.83 | GRM5 (0.68) | GRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL6824566 | 0.82 | MEN1 (0.61) | GRM5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7799604 | 0.82 | MEN1 (0.54) | GRM5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6820557 | 0.82 | TAS1R3 (0.52) | GRM5NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15326419 | 0.81 | L3MBTL1 (1.00) | GRM5L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |