Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720481 | 0.75 | GAA (0.71) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5501345 | 0.74 | POLB (0.42) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL5266671 | 0.74 | POLB (0.41) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30532593 | 0.74 | SMN1; SMN2 (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7832805 | 0.74 | TSHR (0.62) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5507785 | 0.74 | ALOX5 (0.42) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11613235 | 0.73 | GAA (0.51) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11613898 | 0.72 | GAA (0.50) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11614683 | 0.72 | GAA (0.50) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11616556 | 0.72 | GAA (0.50) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |