Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506452 | 0.83 | ALDH1A1 (0.48) | ALOX5ALDH1A1HPGDGAAMAPT | |
| SCHEMBL5504449 | 0.80 | ALOX5 (0.39) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL5505103 | 0.79 | LMNA (0.39) | ALOX5ALDH1A1HPGDGAAMAPT | |
| SCHEMBL5266671 | 0.78 | POLB (0.41) | ALOX5ALDH1A1HPGDGAAMAPT | |
| SCHEMBL5501345 | 0.78 | POLB (0.42) | ALOX5ALDH1A1HPGDGAAMAPT | |
| SCHEMBL5512279 | 0.75 | TLR9 (0.38) | ALOX5ALDH1A1GAAMAPTAR | |
| SCHEMBL334975 | 0.74 | HSD17B10 (0.48) | ALDH1A1HPGDGAAMAPTKDM4E | |
| SCHEMBL4780835 | 0.74 | MAPT (0.55) | ALDH1A1HPGDGAAMAPTKDM4E | |
| SCHEMBL5574004 | 0.73 | KMT2A (0.39) | LMNAKMT2ANEK1 | |
| SCHEMBL1414527 | 0.70 | GAA (0.35) | ALOX5ALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |