Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681203 | 0.81 | AAK1 (0.42) | NFKB1NFKB2RELAUSP30GAA | |
| SCHEMBL6477993 | 0.81 | MAPT (0.48) | DPP4 | |
| SCHEMBL5466436 | 0.81 | MAPT (0.48) | DPP4 | |
| SCHEMBL4775360 | 0.80 | NFKB1 (0.40) | NFKB1NFKB2RELAGAAKDM4D | |
| SCHEMBL4519973 | 0.78 | USP30 (0.36) | USP30GAAKDM4D | |
| SCHEMBL6478544 | 0.76 | MAPT (0.39) | NFKB1NFKB2RELAGAAKDM4D | |
| SCHEMBL5742748 | 0.76 | MAPT (0.39) | NFKB1NFKB2RELAGAAKDM4D | |
| SCHEMBL5462316 | 0.76 | MAPT (0.39) | NFKB1NFKB2RELAGAAKDM4D | |
| SCHEMBL21726933 | 0.76 | CHRM4 (0.40) | CHRM4KDM4D | |
| SCHEMBL18952539 | 0.76 | CHRM4 (0.40) | CHRM4KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |