Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466436 | 1.00 | MAPT (0.48) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL7811564 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL7811560 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL7811566 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6478544 | 0.86 | MAPT (0.39) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL5462316 | 0.86 | MAPT (0.39) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL5742748 | 0.86 | MAPT (0.39) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL13419542 | 0.85 | DRD2 (0.54) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL30915181 | 0.85 | DRD2 (0.54) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6485418 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875784-B2 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | OXA1L, CYP1B1, MT-CO1 | MAPT 2671/4885ALDH1A1 345/4885LMNA 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.