Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797560 | 0.92 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL3515953 | 0.92 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL1797557 | 0.92 | OPRD1 (0.45) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL4781736 | 0.89 | OPRD1 (0.43) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4781848 | 0.88 | OPRD1 (0.53) | OPRD1CYP17A1 | |
| SCHEMBL4794880 | 0.88 | OPRD1 (0.53) | OPRD1CYP17A1 | |
| SCHEMBL4781630 | 0.86 | OPRD1 (0.38) | OPRD1OPRM1OPRK1OPRL1PRCP | |
| SCHEMBL4781704 | 0.83 | CREBBP (0.35) | OPRD1 | |
| SCHEMBL3518323 | 0.79 | SLC6A3 (0.46) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL3516176 | 0.79 | SLC6A3 (0.46) | OPRD1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |