Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794880 | 1.00 | OPRD1 (0.53) | OPRD1KMT2ADPP4DPP7GHSR | |
| SCHEMBL4778904 | 0.90 | OPRD1 (0.46) | OPRD1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8220552 | 0.90 | OPRD1 (0.46) | OPRD1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4781630 | 0.88 | OPRD1 (0.38) | OPRD1DPP4DPP7CYP17A1 | |
| SCHEMBL4834221 | 0.88 | OPRD1 (0.42) | OPRD1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4780979 | 0.88 | OPRD1 (0.48) | OPRD1CYP17A1 | |
| SCHEMBL4725337 | 0.87 | OPRD1 (0.50) | OPRD1KMT2AGHSRCYP17A1ALDH1A1 | |
| SCHEMBL4725329 | 0.87 | OPRD1 (0.50) | OPRD1KMT2AGHSRCYP17A1ALDH1A1 | |
| SCHEMBL4781704 | 0.81 | CREBBP (0.35) | OPRD1DPP4 | |
| SCHEMBL1797557 | 0.80 | OPRD1 (0.45) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |