Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781444 | 0.88 | PIK3CA (0.35) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4784452 | 0.83 | PIK3CA (0.50) | PIK3CAPIK3CBPIK3CGMTORPIK3CD | |
| SCHEMBL4782727 | 0.83 | PIK3CA (0.58) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4785240 | 0.83 | PIK3CA (0.58) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4786681 | 0.83 | POLB (0.40) | PIK3CAPIK3R1 | |
| SCHEMBL14161656 | 0.83 | PIK3CA (0.40) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4785203 | 0.83 | KDR (0.42) | KDRPIK3CAPIK3R1PIK3CBPIK3CG | |
| SCHEMBL14161861 | 0.81 | LMNA (0.37) | PIK3CAPIK3R1PIK3CBPIK3CGKDM4E | |
| SCHEMBL14161859 | 0.80 | PIK3CA (0.38) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4785757 | 0.79 | PIK3CA (0.36) | PIK3CAPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |