Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992292 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNAHTTMAPK1 | |
| Fumaric Acid SCHEMBL10926982 | 0.82 | NPC1 (0.40) | ALDH1A1TSHRLMNAHTTMAPK1 | |
| Maleic Acid SCHEMBL10926977 | 0.82 | NPC1 (0.40) | ALDH1A1TSHRLMNAHTTMAPK1 | |
| SCHEMBL3853732 | 0.81 | KDM4E (0.44) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL10925378 | 0.80 | KMT2A (0.44) | ALDH1A1KMT2AMEN1NPC1HPGD | |
| SCHEMBL10925296 | 0.78 | ATM (0.39) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| SCHEMBL10992668 | 0.77 | MAPT (0.50) | ALDH1A1TSHRLMNAKMT2ANPC1 | |
| SCHEMBL10926602 | 0.75 | NPC1 (0.56) | ALDH1A1TSHRLMNAHTTMAPK1 | |
| SCHEMBL1324894 | 0.74 | POLB (0.48) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL4726217 | 0.73 | MEN1 (0.40) | ALDH1A1TSHRLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |