Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10926982 | 0.93 | NPC1 (0.40) | ALDH1A1LMNANPC1KMT2ATSHR | |
| Maleic Acid SCHEMBL10926977 | 0.93 | NPC1 (0.40) | ALDH1A1LMNANPC1KMT2ATSHR | |
| SCHEMBL4781509 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNANPC1KMT2ATSHR | |
| SCHEMBL10992668 | 0.82 | MAPT (0.50) | ALDH1A1LMNANPC1KMT2ATSHR | |
| SCHEMBL10927176 | 0.81 | LTA4H (0.41) | LMNANPC1KMT2ATSHRLTA4H | |
| SCHEMBL10925925 | 0.80 | MAPT (0.41) | LMNANPC1KMT2ATSHRLTA4H | |
| SCHEMBL10922342 | 0.79 | LTA4H (0.39) | NPC1KMT2ATSHRLTA4HMAPT | |
| SCHEMBL10927504 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1LMNANPC1KMT2ATSHR | |
| SCHEMBL27035210 | 0.75 | NPC1 (0.64) | ALDH1A1LMNANPC1TSHRMAPT | |
| SCHEMBL10923767 | 0.73 | THRB (0.44) | ALDH1A1LMNANPC1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |