Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782298 | 0.81 | SMYD3 (0.40) | GLS | |
| SCHEMBL4780340 | 0.76 | DPP4 (0.42) | GLSMGAMGAASIMGAM2 | |
| SCHEMBL4781030 | 0.76 | MGAM (0.56) | GLSMGAMGAASIMGAM2 | |
| SCHEMBL31162000 | 0.70 | GLS (0.52) | GLS | |
| SCHEMBL31162029 | 0.70 | GLS (0.52) | GLS | |
| SCHEMBL25514751 | 0.70 | PSMB8 (0.43) | GLSMGAMGAASIMGAM2 | |
| SCHEMBL4781428 | 0.66 | ADORA2A (0.37) | — | |
| SCHEMBL18900639 | 0.66 | DPP4 (0.37) | — | |
| SCHEMBL17354810 | 0.66 | DPP4 (0.37) | — | |
| SCHEMBL22062686 | 0.65 | DPP4 (0.46) | GLSMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |