Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22062686 | 0.88 | DPP4 (0.46) | DPP4MGAMGAASIMGAM2 | |
| SCHEMBL20364767 | 0.84 | DPP4 (0.39) | DPP4MGAMGAASIMGAM2 | |
| SCHEMBL20615481 | 0.83 | DPP4 (0.40) | DPP4MGAMGAASIMGAM2 | |
| SCHEMBL4781030 | 0.82 | MGAM (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL31124067 | 0.81 | DPP4 (0.49) | DPP4MGAMGAASIMGAM2 | |
| SCHEMBL20368825 | 0.78 | DPP4 (0.36) | DPP4MGAMGAASIMGAM2 | |
| SCHEMBL6072289 | 0.78 | ALDH1A1 (0.45) | DPP4GAAALDH1A1LMNAMAPK1 | |
| SCHEMBL19050263 | 0.77 | DPP4 (0.43) | DPP4GLSCA5A | |
| SCHEMBL4781660 | 0.76 | GLS (0.41) | MGAMGAASIMGAM2GLS | |
| SCHEMBL29224209 | 0.76 | DPP4 (0.42) | DPP4MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |