Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411806 | 0.83 | ELANE (0.55) | CPT2CPT1ACPT1BSTING1TP53 | |
| SCHEMBL9379594 | 0.82 | DRD2 (0.55) | CPT2CPT1ACPT1BSTING1TP53 | |
| SCHEMBL1238062 | 0.82 | POLB (0.47) | POLBLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9209496 | 0.82 | STING1 (0.37) | CPT2CPT1ACPT1BSTING1TP53 | |
| SCHEMBL31411563 | 0.81 | PARK7 (0.54) | CPT2CPT1ACPT1BTP53CYP3A4 | |
| SCHEMBL2242021 | 0.80 | CPT1A (0.48) | CPT2CPT1ACPT1BSTING1LMNA | |
| SCHEMBL22043973 | 0.80 | STING1 (0.50) | POLBCPT2CPT1ACPT1BSTING1 | |
| SCHEMBL22043971 | 0.80 | STING1 (0.53) | POLBCPT2CPT1ACPT1BSTING1 | |
| SCHEMBL9142318 | 0.80 | LMNA (0.46) | CPT2CPT1ACPT1BLMNACYP26A1 | |
| SCHEMBL25943106 | 0.79 | STING1 (0.62) | POLBCPT2CPT1ACPT1BSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017465-A1 | BICYCLIC LACTAM DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-14 | — | — | WO | claimed |
| WO-2008017465-A1 | BICYCLIC LACTAM DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-14 | — | — | WO | disclosed |
| US-5414088-A | Anticoagluants | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-09 | — | — | US | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| CN-1038640-A | Two ring carboxamide, its preparation methods and contain the pharmaceutical composition of this material | BOEHRINGER MANNHEIM GMBH (DE) | 1990-01-10 | — | — | CN | disclosed |