Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497176 | 0.87 | RXRA (0.44) | RXRBRXRARXRGL3MBTL1PLK1 | |
| SCHEMBL4782119 | 0.87 | L3MBTL1 (0.43) | L3MBTL1PLK1S1PR1S1PR3CA12 | |
| SCHEMBL25301433 | 0.87 | RXRA (0.44) | RXRBRXRARXRGL3MBTL1PLK1 | |
| SCHEMBL4904528 | 0.85 | PLK1 (0.44) | L3MBTL1PLK1S1PR1S1PR3CA12 | |
| SCHEMBL25301459 | 0.82 | TPMT (0.50) | RXRBRXRAL3MBTL1PLK1CA12 | |
| SCHEMBL31362829 | 0.82 | TPMT (0.50) | RXRBRXRAL3MBTL1PLK1CA12 | |
| SCHEMBL19131016 | 0.80 | S1PR1 (0.59) | RXRBRXRARXRGS1PR1S1PR3 | |
| SCHEMBL14752302 | 0.79 | L3MBTL1 (0.46) | L3MBTL1PLK1CA12CA1CA2 | |
| SCHEMBL25301375 | 0.79 | L3MBTL1 (0.50) | RXRBRXRAL3MBTL1PLK1CA12 | |
| SCHEMBL30497207 | 0.79 | L3MBTL1 (0.50) | RXRBRXRAL3MBTL1PLK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |