Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600674 | 0.84 | ERCC5 (0.72) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL28771856 | 0.80 | ERCC5 (0.67) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL21995821 | 0.79 | ERCC5 (0.55) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL4716770 | 0.78 | ERCC5 (0.70) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL29113253 | 0.78 | ERCC5 (0.64) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL908578 | 0.77 | ERCC5 (0.62) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL21414950 | 0.77 | RAB9A (0.69) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL11606610 | 0.77 | KMT2A (0.74) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL599285 | 0.77 | KMT2A (0.74) | ERCC5FEN1GSK3BMAPTL3MBTL1 | |
| SCHEMBL11606030 | 0.77 | ERCC5 (0.62) | ERCC5FEN1GSK3BMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |