Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.64 |
| ▸ | FEN1 | P39748 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271455 | 0.91 | MEN1 (0.52) | ERCC5FEN1GSK3BMAPTKDM4E | |
| SCHEMBL600674 | 0.88 | ERCC5 (0.72) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL28771856 | 0.84 | ERCC5 (0.67) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL4716770 | 0.82 | ERCC5 (0.70) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL599285 | 0.80 | KMT2A (0.74) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL908578 | 0.80 | ERCC5 (0.62) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL11606610 | 0.80 | KMT2A (0.74) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL28874706 | 0.80 | GSK3B (0.87) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL21414950 | 0.80 | RAB9A (0.69) | ERCC5FEN1GSK3BL3MBTL1MAPT | |
| SCHEMBL28991602 | 0.80 | PLOD2 (0.60) | MAPTKDM4ECES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126119-A | Preparation method of (benzo) thiazole amide-containing compound | 济宁医学院 | 2023-11-28 | — | — | CN | disclosed |