SCHEMBL599285

SCHEMBL599285

O=C(CC(=O)c1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.74
MAPT P10636 5/20 0.74
MEN1 O00255 5/20 0.74
HPGD P15428 4/20 0.74
MAPK1 P28482 3/20 0.74
ALOX15 P16050 3/20 0.74
CES1 P23141 2/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
CYP3A4 P08684 2/20 0.74
KDM4E B2RXH2 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
ERCC5 P28715 2/20 0.68
FEN1 P39748 2/20 0.68
NPC1 O15118 3/20 0.68
RAB9A P51151 3/20 0.68
L3MBTL1 Q9Y468 2/20 0.66
CES2 O00748 1/20 0.65
USP2 O75604 1/20 0.64
LMNA P02545 1/20 0.64
TP53 P04637 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11606610 1.00 KMT2A (0.74) KMT2AMAPTMEN1HPGDMAPK1
SCHEMBL28972876 0.92 KMT2A (0.63) KMT2AMAPTMEN1HPGDMAPK1
SCHEMBL600674 0.91 ERCC5 (0.72) KMT2AMAPTMEN1HPGDMAPK1
SCHEMBL2005451 0.89 MEN1 (0.94) KMT2AMAPTMEN1HPGDMAPK1
Dibenzoylmethane SCHEMBL31675817 0.89 KMT2A (0.94) KMT2AMAPTMEN1HPGDMAPK1
SCHEMBL11056976 0.88 KMT2A (0.60) KMT2AMAPTMEN1HPGDMAPK1
SCHEMBL28372673 0.87 L3MBTL1 (0.72) KMT2AMAPTMEN1HPGDMAPK1
Dibenzoylmethane SCHEMBL1704711 0.86 MEN1 (1.00) KMT2AMAPTMEN1HPGDMAPK1
Dibenzoylmethane SCHEMBL39582 0.86 MEN1 (1.00) KMT2AMAPTMEN1HPGDMAPK1
Dibenzoylmethane SCHEMBL10356288 0.86 MEN1 (1.00) KMT2AMAPTMEN1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117440805-A Method for treating nonalcoholic steatohepatitis by co-administration of curcumin derivative and TGF-beta receptor inhibitor 延世大学校原州产学协力团 2024-01-23 CN claimed
WO-2022270760-A1 METHOD FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS THROUGH CO-ADMINISTRATION OF CURCUMIN DERIVATIVE AND TGF-Β RECEPTOR INHIBITOR 연세대학교 원주산학협력단 2022-12-29 WO claimed
CN-105523874-A Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2016-04-27 CN claimed
CN-105503635-A Preparation method for 2-amidoformyl-1,3-dicarbonyl derivative UNIV SOOCHOW 2016-04-20 CN claimed
CN-105503945-A Method for preparing 2-phosphonic acid ester base-1, 3-dicarbonyl derivative UNIV SOOCHOW 2016-04-20 CN claimed
CN-105461496-A Preparation method for 2-halogenated-1,3-dicarbonyl derivative CHINASUN SPECIALTY PRODUCTS CO LTD 2016-04-06 CN claimed
CN-105254483-A Method for preparing 2-methyl-1,3-dicarbonyl derivative UNIV SOOCHOW 2016-01-20 CN claimed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
JP-56036536-A None JP disclosed
JP-63152654-A None JP disclosed
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION AKDENIZ CHEMSON ADDITIVES A.G. (AT) 2026-05-28 US disclosed
EP-4605200-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION Akdeniz Chemson Additives AG (AT) 2025-08-27 EP disclosed
CN-120076911-A Method and device for producing a stabilizer composition in particulate form and stabilizer composition produced thereby 阿登尼斯开米森添加剂股份公司 2025-05-30 CN disclosed
EP-0035268-A1 Chlorinated organic compounds having their resistance to deterioration enhanced by 1,3-dicarbonyl compounds ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-09-09 EP disclosed
US-4282141-A DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1981-08-04 US disclosed
JP-S5636536-A STABLIZED HALOGEN-CONTAINING RESIN COMPOSITION ADEKA ARGUS CHEM CO LTD 1981-04-09 JP disclosed
US-4252698-A A OVERBASED SULFONATE OR PHENOLATE, AND A 1,3-DIKETONE FOR VINYL CHLORIDE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1981-02-24 US disclosed
US-4244848-A HEAT RESISTANT STABILIZERS COMPRISING AT LEAST ONE ZINC, DIALKYLTIN, ALKALI METAL OR ALKALINE EARTH METAL ORGANIC PHOSPHATE ESTER SALT AND AT LEAST ONE B-DIKETONE ARGUS CHEMICAL CORPORATION (US) 1981-01-13 US disclosed
US-3932182-A An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group MITSUBISHI PAPER MILLS, LTD. (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260145365-A1 METHOD AND DEVICE FOR PRODUCING A STABILIZER COMPOSITION IN GRANULATE FORM AND AN ACCORDINGLY PRODUCED STABILIZER COMPOSITION GRN, IL36G, GMNN KMT2A 4384/4885MAPT 547/4885MEN1 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.