Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784263 | 0.90 | MEN1 (0.47) | TSHRL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL4734599 | 0.79 | POLB (0.48) | TSHRTBXAS1PKMMEN1KMT2A | |
| SCHEMBL4733942 | 0.76 | POLB (0.48) | TSHRTBXAS1L3MBTL1 | |
| SCHEMBL4732951 | 0.74 | ALDH1A1 (0.41) | TSHRTBXAS1 | |
| SCHEMBL4732291 | 0.74 | POLB (0.38) | TSHRTBXAS1L3MBTL1 | |
| SCHEMBL4731034 | 0.73 | POLB (0.37) | TSHRTBXAS1L3MBTL1 | |
| SCHEMBL4734886 | 0.72 | POLB (0.45) | TSHRTBXAS1 | |
| SCHEMBL4796983 | 0.71 | SMN1; SMN2 (0.38) | TSHRTBXAS1 | |
| SCHEMBL4781080 | 0.70 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL4733104 | 0.70 | POLB (0.42) | TSHRTBXAS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |