Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782445 | 0.90 | TSHR (0.43) | MEN1KMT2APKML3MBTL1TSHR | |
| SCHEMBL4785131 | 0.74 | MEN1 (0.35) | MEN1KMT2AALDH1A1PKM | |
| SCHEMBL4732136 | 0.73 | MEN1 (0.47) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL4781080 | 0.71 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL4734599 | 0.71 | POLB (0.48) | MEN1KMT2AALDH1A1HTTPKM | |
| SCHEMBL4729813 | 0.70 | SFRP1 (0.50) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL11174127 | 0.65 | TDP1 (0.64) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL4732291 | 0.64 | POLB (0.38) | ALDH1A1HTTL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL4732951 | 0.64 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL4734109 | 0.64 | MEN1 (0.43) | MEN1KMT2ATDP1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |