Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783455 | 0.89 | GAA (0.36) | ALDH1A1NPSR1GAAMMP2MAPT | |
| SCHEMBL4530837 | 0.77 | EPHX2 (0.44) | ALDH1A1NPSR1GAAMMP2ITGB2 | |
| SCHEMBL4532058 | 0.72 | POLB (0.51) | ALDH1A1GAAMMP2KDM4ELMNA | |
| SCHEMBL13964809 | 0.67 | HCRTR1 (0.51) | GAAUSP2MAPTTDP1LMNA | |
| SCHEMBL3825925 | 0.65 | PLAU (0.51) | ALDH1A1GAA | |
| SCHEMBL719443 | 0.63 | FABP3 (0.41) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1005423 | 0.61 | FABP3 (0.40) | LMNA | |
| Ammonia Solution, Strong SCHEMBL11578768 | 0.61 | FABP3 (0.40) | LMNA | |
| SCHEMBL971368 | 0.61 | L3MBTL1 (0.32) | ALDH1A1 | |
| SCHEMBL23519440 | 0.60 | FKBP1A (0.69) | ALDH1A1NPSR1GAAMMP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985624-A2 | Single step method of radiofluorination of biologically active compounds or biomolecules | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |