Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 8/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782536 | 0.89 | ALDH1A1 (0.36) | GAAMMP2ADAM17ALDH1A1NPSR1 | |
| SCHEMBL4526832 | 0.78 | EPHX2 (0.43) | GAAMMP2ADAM17ALDH1A1 | |
| SCHEMBL4529431 | 0.74 | MMP2 (0.56) | MMP2ALDH1A1POLB | |
| SCHEMBL13964804 | 0.70 | HCRTR1 (0.51) | GAAMAPTPOLB | |
| SCHEMBL4530837 | 0.67 | EPHX2 (0.44) | GAAMMP2ALDH1A1NPSR1 | |
| SCHEMBL23519455 | 0.63 | TDP1 (0.64) | GAAMMP2MMP9ALDH1A1NPSR1 | |
| SCHEMBL3825925 | 0.62 | PLAU (0.51) | GAAMMP1MMP13MMP9ALDH1A1 | |
| SCHEMBL13964809 | 0.62 | HCRTR1 (0.51) | GAAMAPTTDP1POLB | |
| SCHEMBL719443 | 0.61 | FABP3 (0.41) | ALDH1A1TRPA1 | |
| SCHEMBL9425114 | 0.61 | SLC9A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985624-A2 | Single step method of radiofluorination of biologically active compounds or biomolecules | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |