Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 16/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784742 | 0.94 | PIK3CA (0.42) | LMNAMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL4786822 | 0.91 | HSD17B10 (0.42) | LMNAMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL4785045 | 0.85 | PIK3CA (0.39) | — | |
| SCHEMBL4785055 | 0.85 | PIK3CA (0.39) | — | |
| SCHEMBL4785891 | 0.84 | PIK3CA (0.46) | LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL4782543 | 0.83 | DGAT2 (0.42) | DGAT2LMNAMAPK1MAPTHSD17B10 | |
| SCHEMBL4782397 | 0.82 | PIK3CA (0.39) | — | |
| SCHEMBL4782625 | 0.81 | PIK3CA (0.40) | — | |
| SCHEMBL4782618 | 0.81 | PIK3CA (0.40) | — | |
| SCHEMBL4786374 | 0.81 | KDM4E (0.44) | LMNAMAPK1MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |