Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782541 | 0.91 | DGAT2 (0.40) | HSD17B10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4784742 | 0.88 | PIK3CA (0.42) | HSD17B10ALDH1A1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL4785055 | 0.87 | PIK3CA (0.39) | IDH2PIK3CAPIK3CBESR1ESR2 | |
| SCHEMBL4785045 | 0.87 | PIK3CA (0.39) | IDH2PIK3CAPIK3CBESR1ESR2 | |
| SCHEMBL4782397 | 0.84 | PIK3CA (0.39) | IDH2PIK3CAESR1ESR2 | |
| SCHEMBL4782618 | 0.84 | PIK3CA (0.40) | PIK3CAPIK3CDPIK3CBPIK3CGESR1 | |
| SCHEMBL4782625 | 0.84 | PIK3CA (0.40) | PIK3CAPIK3CDPIK3CBPIK3CGESR1 | |
| SCHEMBL4786826 | 0.82 | KDM4E (0.43) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4784691 | 0.82 | AOC3 (0.41) | PIK3CAESR1ESR2 | |
| SCHEMBL4783343 | 0.82 | AOC3 (0.41) | PIK3CAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |