Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670660 | 0.79 | ADORA2B (0.35) | ADORA2BGLABLMADORA3PARG | |
| SCHEMBL4670663 | 0.68 | ADORA2B (0.60) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL4792983 | 0.67 | ADORA2A (0.41) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL4792980 | 0.67 | ADORA2B (0.36) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL4782544 | 0.67 | ADORA2B (0.36) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL2578107 | 0.65 | ALDH1A1 (0.35) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL2570140 | 0.65 | ADORA2B (0.47) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL2546553 | 0.64 | ADORA2B (0.47) | ADORA2BGLABLMADORA3ADORA2A | |
| SCHEMBL8004119 | 0.62 | TNF (0.40) | ADORA2BBLMADORA2A | |
| SCHEMBL2556027 | 0.61 | ADORA2B (0.40) | ADORA2BGLABLMADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |