Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570140 | 0.82 | ADORA2B (0.47) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL2556027 | 0.78 | ADORA2B (0.40) | ADORA2AADORA2BGLABLMADORA1 | |
| SCHEMBL2546553 | 0.73 | ADORA2B (0.47) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL4782546 | 0.67 | ADORA2B (0.34) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL4781818 | 0.67 | ADORA1 (0.42) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4670663 | 0.67 | ADORA2B (0.60) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL4670660 | 0.65 | ADORA2B (0.35) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL2578107 | 0.64 | ALDH1A1 (0.35) | ADORA2AADORA2BGLABLMADORA3 | |
| SCHEMBL2547498 | 0.64 | ADORA2B (0.47) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL2546554 | 0.62 | ADORA2B (0.48) | ADORA2AADORA2BGLABLMADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |