Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659307 | 0.79 | MEN1 (0.65) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL2640927 | 0.79 | MEN1 (0.69) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL966694 | 0.79 | MEN1 (0.69) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL5995235 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11617583 | 0.77 | MEN1 (0.67) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL965733 | 0.77 | MEN1 (0.67) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL4294745 | 0.77 | MEN1 (0.67) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL4304223 | 0.76 | MEN1 (1.00) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11223447 | 0.75 | EGFR (0.53) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11221787 | 0.75 | EGFR (0.53) | MEN1KMT2AALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075064-A1 | PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |