Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 6/20 | 0.50 |
| ▸ | FLT4 | P35916 | 6/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221787 | 0.86 | EGFR (0.53) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL7838561 | 0.81 | FLT1 (0.54) | EGFRERBB2FLT1FLT4KDR | |
| SCHEMBL7836330 | 0.81 | FLT1 (0.50) | EGFRERBB2FLT1FLT4KDR | |
| SCHEMBL7833152 | 0.77 | FLT1 (0.50) | EGFRERBB2FLT1FLT4KDR | |
| SCHEMBL25297441 | 0.77 | ALDH1A1 (0.57) | EGFRERBB2FLT1FLT4KDR | |
| SCHEMBL7835295 | 0.76 | KDM4E (0.46) | EGFRERBB2MEN1KMT2ALMNA | |
| SCHEMBL4782949 | 0.75 | MEN1 (0.61) | L3MBTL1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20016685 | 0.74 | MEN1 (0.79) | L3MBTL1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11566550 | 0.74 | KDM4E (0.54) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL11050968 | 0.73 | CYP3A4 (0.54) | MEN1KMT2AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365990-A | Sulfonylurea herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4260824-A | Sulfonylurea herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-04-07 | — | — | US | disclosed |